Endocrine Abstracts

Introduction: Abiraterone acetate, potent selective irreversible inhibitor of CYP17A1, is increasingly used with prednisone to treat prostate cancer resistant to androgen deprivation therapy.Case Presentation: 64-year-old gentleman with BG of prostate cancer with widespread metastatic bone disease. He was on abiraterone since 2019. Admitted with generally unwell, aches/pains, headache, and dizziness. Euvolemic hyponatrem...

Introduction: Acute Colonic Pseudo-Obstruction (Ogilvie’s syndrome) is characterized by colonic distention in the absence of mechanical obstruction. Those without ischaemia/perforation is treated conservatively by withdrawing offending drugs, correcting electrolytes/underlying risk factors, neostigmine and colonic decompression.Case Presentation: 90-year-old frail lady from care home with HTN, CVA, and dementia, adm...

Introduction: EAS is an endocrine emergency requiring emergency diagnosis/treatment. Bronchial carcinoid is known to cause EAS and carcinoid syndrome (without liver involvement).Clinical features: 58-year-old lady with COPD and fibromyalgia referred as 2WW pathway with abdominal pain, diarrhoea, and weight loss. Investigated with CT-CAP: inflammatory looking 7mm lung nodule left upper lobe, enlarged left hilar, aorto-pul...

Introduction: Thyroid storm presents as multiorgan dysfunction. Diagnosis is purely clinical, and early diagnosis improves the outcomes.Case Presentation: 45-year-old lady without significant illness presented with breathlessness, productive cough, anxiety, and weight loss. Chest x-ray showed right pleural effusion and left consolidation. She was in fast AF with NT-proBNP >27000. initially treated as chest sepsis wit...

Introduction: AIT1 usually occur on a background of Graves’ disease or toxic nodule goitre. The disease usually requires higher doses of carbimazole than Graves’, might need rescue thyroidectomy, and can be treated with radioiodine with higher than standard radioiodine doses after iodine contamination has come down.Case Presentation: 57-year-old gentleman with history of HTN, T2DM, dyslipidemia, aortic stenosis...